Rasmus Blendal, SMART-TRIAL writes that Electronic Data Capture (EDC) systems will likely never measure up to our expectations, despite EDC systems being made to replace the Paper CRF. He discusses the first, second and third waves of EDC systems (remote data entry, the internet, and software-as-a-service). Blendal concludes with the future of EDC systems, with the next wave being what he sees as potentially ending paper within clinical trials.