Each year, Veeva surveys the pharmaceutical industry on its use of trial master file (TMF) processes. Within this article, Rik van Mol, Vice President of R&D Strategy, Europe, at Veeva Systems, explains that the Veeva 2016 Paperless TMF Survey features feedback from 217 TMF managers worldwide. It shows a significant change is under way as the industry shifts from passive to active TMF management and adopts advanced electronic TMF (eTMF) applications.