The diagnosis of movement disorders and neurodegenerative diseases can be problematic for clinicians and radiologists alike. There is considerable overlap in the early presentation of these diseases especially when tremor is absent or atypical in character. Routine anatomic imaging is insensitive and early imaging findings are typically absent or non-specific. Dr. Barry Menick from Intrinsic Imaging deals with Parkinson`s disease, by mentioning the Dopamin as well.