Current Edition

Industry and Academia Partnering to Advance Prevention and Treatment of Alzheimer’s Disease

As Markku Toivonen, MD, PhD, chairman of CHMP Scientific Advice Working Party, explains in this piece, according to current evidence, Alzheimer’s disease (AD) is a disease continuum with a 10-20-year pre-symptomatic phase preceding the onset of dementia. The International Working Group (IWG) on research diagnostic criteria for AD provided in 2007 a new framework, where the presence of biomarkers characteristic of AD, albeit not mandatory for diagnosis, provides additional proof of diagnosis in the absence of clear clinical manifestations.