Jayne Abraham, PhD, Director of Medical and Scientific Affairs for Neuroscience at Worldwide Clinical Trials Therapeutic and Idil Çavuş, MD PhD is a Senior Medical Director of Medical and Scientific Affairs for Neuroscience at Worldwide Clinical Trials explain how rare diseases cover a broad range of diseases and patients, with about 50% of those affected being children. Many have a genetic component, while others arise from exposure to infections or toxins, from faulty immune responses, or occasionally from trauma or injury (e.g. traumatic brain injury (TBI)).
https://www.jforcs.com/7/wp-content/uploads/2016/07/Improving-Development.pdf