Patient recruitment costs around 6-7% of the total and it is highest among all other cost components. Almost 80% of clinical trials are delayed due to patient recruitment challenges. This delay adds on to the cost of maintaining staff and site, and shortening the patent period. These issues are pushing clinical trials towards two major shifts. Shift from Patient recruitment to Patient engagement and shift from site centric trials to Patient centric trials. We have an insight into these shifts by Nandini Nema of Beroe Inc.